Web8 sep. 2024 · Hyperpolarized [1- 13 C]pyruvate magnetic resonance spectroscopic imaging (MRSI) is a noninvasive metabolic-imaging modality that probes carbon … Web16 jun. 2024 · This study uses dynamic hyperpolarized [1-13 C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer models.
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WebAbstract. The source of hyperpolarized (HP) [ (13)C]bicarbonate in the liver during metabolism of HP [1- (13)C]pyruvate is uncertain and likely changes with physiology. … Web5 mrt. 2024 · Hyperpolarized (HP) 13 C MRI has emerged as a powerful molecular imaging strategy that allows safe, nonradioactive, real-time, and pathway-specific investigation of … jeremy camp new song 2021
(PDF) HYPERPOLARIZATION OF PYRUVATE DERIVATIVES USING …
Web[1-13C]pyruvate, the most widely used compound in dissolution-dynamic nuclear polarization (dDNP) magnetic resonance (MR), enables the visualization of lactate dehydrogenase (LDH) activity. This activity had been demonstrated in a wide variety of cancer models, ranging from cultured cells, to xenograft models, to human tumors in situ. … Web28 jan. 2024 · Pyruvate labelled with 13 C in the carboxyl position ([1-13 C]pyruvate) is most frequently used in vivo for hyperpolarised 13 C-MRI, as the time constant for loss of the hyperpolarised signal (T 1... Web10 okt. 2024 · Given conflicting reports in the literature about the degree of transport of hyperpolarized pyruvate across the blood-brain barrier in naive and diseased brain in … jeremy camp music youtube