WebSep 22, 2024 · Cathepsin B (CTSB), a lysosomal cathepsin, is involved in cell autophagy and apoptosis. In this study, Liu C et al. found that CTSB was increased in diabetic … WebJun 21, 2024 · Lysosomal cathepsin B (CTSB) has been proposed to play a role in the induction of acute inflammation. We hypothesised that the presence of active CTSB in the cytosol is crucial for NLRP3-inflammasome assembly and, consequently, for mature IL-1β generation after mycobacterial infection in vitro. Elevated levels of CTSB was observed …
人乳腺癌细胞的应用
WebApr 10, 2024 · NLRP3炎症体发挥作用的相关调控机制. 氧化应激反应与NLRP3炎症体的激活氧化应激是指机体遭受各种刺激时体内氧化与抗氧化作用失衡,大量氧化产物堆积,导 … WebFeb 27, 2024 · CTSB (cathepsin B) plays an important role in Mn-induced NLRP3-CASP1 in fl ammasome activation, and that the increased autophagosomes in the cytoplasm are not the main cause of NLRP3-CASP1 in fl ... dave cunningham attorney rock island
人乳腺癌细胞的应用
WebApr 6, 2024 · ALDOC (fructose-bisphosphate aldolase C) is a glycolytic protein that among other functions has been reported in neutrophil degranulation, and was shown to be decreased in AD brain entorhinal cortex. 36 CTSB is a lysosomal cysteine protease that can play a role in neutrophil degranulation 37 was described as a driver of microglial … WebHowever, the dissolved and ruptured lysosomes are found to release Cathepsin B (CTSB), which may activate the assembly of the NLRP3 inflammasome. CTSB is a ubiquitous cysteine cathepsin mainly located in lysosomes and plays crucial roles in various physiological processes, such as inflammation, immune response, apoptosis, and … WebApr 4, 2024 · Lamp1, Lamp2, Ctsb, Ctss (cathepsin S), Nlrp3, and other genes related to the lysosomal damage pathway were significantly increased in NP-fed mice compared with those in untreated mice (Figure 3G). By analyzing the Kyoto Encyclopedia of Genes and Genomes (KEGG) ... black and gold tea